Effectiveness of non-magnetic ions Doping on optical energy, surface properties and antimicrobial activity of Ba-Based nanoferrites

Abstract

 The current study was invented to investigate the main mechanism of barium hexaferrite nanoparticles (BFNPs) as antibacterial activity. In this concern, barium-nickel ferrite doped by zinc ions has been synthesized by a ceramic method. The x-ray  results are evidence the average crystallite size and surface area   showed that the sample Zn=0.4   had a smaller crystallite size and a high specific surface area than other samples. The decrease in energy band gap for this sample also, confirmed from UV results, which is useful to find a relationship between band gap and antibacterial activity so as to migrate electron from valence band to conduction band. The antibacterial activity against two different types of Gram-positive and Gram-negative bacteria was examined using the powder concentrations of the BFNPs. At the higher concentration range of 3 mL, all nanoparticles exhibited inhibition against both gram-positive and gram-negative bacteria. The antibacterial results reveal a low (16 mm) impact on Bacillus subtilis growth and a high (30 mm) impact on Pseudomonas aeruginosa. The difference in antibacterial activity against Gram-positive and Gram-negative bacteria may be caused by the composition of the cell walls and variations in how the membrane interacts with the cell at the molecular and cellular levels. Additionally, the antibacterial activity is significantly influenced by nanoparticle size, microstructure, and specific surface area. Cell membrane damage, protein leaks, and intracellular reactive oxygen species production have all been identified as components of the underlying antimicrobial mechanism. This research shows that barium nickel ferrite PFNs may be a suitable material for biomedical applications and an effective antibacterial candidate.