Chronic Kidney Disease in Yemeni Patients with Acute Heart Failure

Abstract

Background: Chronic kidney disease (CKD) represents a major health problem in Yemen that has great socioeconomic and medical con-sequences. (A) It associates with comorbid conditions, such as hypertension, diabetes and cardiovascular disease (B). Heart failure (HF) is highly prevalent in patients with (CKD) and increases greatly as the patient's renal function deteriorates, and can reach 65-70% in end-stage renal disease (ESRD) with increase mortality in these patients.   Aims: To show the impact of different degrees of renal impairment on heart failure (HF) in Yemeni patients. methods: Gulf CARE is a prospective, multicenter, multinational registry of patients >18 year of age admitted with diagnosis of acute HF (AHF). The data collected included demographics, clinical characteristics, etiology, precipitating factors, management and outcomes of patients admitted with AHF. In addition, data about hospital readmission rates, procedures and mortality at 3 months and 1 year follow up were recorded. Hospital characteristics and care provider details were collected.   Results:   Total of (no.) 30.7      % of Yemeni patients with HF had eGFR <60 mL /min/1.73m2 , while  (no.)   3.5     % had eGFR <30 mL /min/1.73m2. End Stage Renal Disease ( ESRD )with  eGFR <15 mL /min/1.73m2 was documented in    2.5 % of the patients . High mortality were noted among  HF patients with chronic kidney disease ( CKD ). There were a big association between the degree of renal impairment ,  the severity of HF and the age of the patient with P value of <0.001. Conclusion: CKD is highly linked to the severity of HF and its short and long terms outcomes.